Streptococcus pneumoniae and neisseria meningitidis. Bacterial meningitis is a leading cause of death from infectious disease worldwide. Meningitis meninjietiss is an infection of the meninges meninjeez. Having less than 100 wbcs per mm3 is more common in patients with viral. Acute bacterial meningitis in adults the hospitalist. Chandramuki department of neuromicrobiology, national institute of mental heal th and neurosciences nimhans, bengaluru karnataka, india 1. Laboratorial diagnosis of lymphocytic meningitis scielo. The use of csf for other purposes including the diagnosis of specific. Bacterial meningitis is a medical emergency requiring immediate diagnosis and immediate treatment.
Classic features of bacterial meningitis, such as stiff neck and fever, may be absent. Introduction meningitis is an infection of the membranes meninges surrounding the brain and spinal cord. Your family doctor or pediatrician can diagnose meningitis based on a medical history, a physical exam and certain diagnostic tests. Csf protein in l y m e meningitis is stated to be almost invariably raisedf19 in our cases also, the csf protein values were significantly higher in l y m e meningitis than in the n o n l y m e patients. Csf findings is highly suggestive of meningitis and helpful in determining the likely etiology table 3. Printer friendly version cdc pdf 26 pages microbiology laboratories commonly receive cerebrospinal fluid csf or blood specimens from patients with meningitis, pneumonia, or unexplained febrile illness. Laboratories may also receive joint fluid, pleural fluid, or other sterile site specimens from these patients. This should be considered as a differential when suspecting aseptic viral meningitis. The recertification process ensures ncsf board certified professionals maintain compliance with current practice standards and adhere to the ethical code of conduct. For clinical guidelines, we accessed the websites of the uk health protection agency. In fact, meningitis may come on the heels of a flulike illness or. Confirmed viral meningitis with normal csf findings. While these physical examination findings may be of value in determining the diagnosis of bacterial meningitis, the accuracy of the clinical history including features such as headache, nausea and vomiting, and neck pain was too low to be of use clinically.
Diagnosis, initial management, and prevention of meningitis. These are the membranes that cover the brain and spinal cord picture 1. Meningitis occurs when the membranes that cover the brain and spinal cord become inflamed. Csf findings may be suggestive see csfinterpretation guideline. Viral meningitis meningoencephalitis accounted for the majority of cases of lymphocytic csf in the caucasian subgroup. If there is a high clinical suspicion of meningitis, children who have a normal csf. It demonstrates your commitment to competency and communicates professionalism to your clients, peers, employers, and the community you serve. Practice guidelines for acute bacterial meningitidis.
Characteristic csf findings for bacterial meningitis consist of polymorphonuclear pleocytosis, hypoglycorrhachia, and raised csf protein levels. Empiric antibiotics treatment without exact diagnosis should be started immediately, even before the results of the lumbar puncture and csf analysis are known. When allowed to progress without treatment, coma and death almost always ensue. In survivors of tbm, neurologic sequelae may occur that include mental retardation in children, sensorineural hearing loss, hydrocephalus. People often confuse the early signs and symptoms of meningitis with the flu.
The commonest organisms causing bacterial meningitis in children over 2 months of age. When there is clinical suspicion of meningitis, analysis of the csf is mandatory. The neurological complications secondary to bacterial meningitis contribute to the high mortality rate and to. Nuchal rigidity had a sensitivity of 70%, and mental status change was 67%. Meningitis lab manual primary culture and presumptive. Clinical features alone cannot confirm the diagnosis of meningitis. The 2016 uk meningitis guidelines recommend an lp be performed without prior.
Complications and outcome of bacterial meningitis research. Pathophysiology and treatment of bacterial meningitis ncbi. This is normally caused by infection but can also have non. British infection society guidelines for the diagnosis and treatment of. We have presented guidance on tuberculous meningitis tbm, intracerebral tuberculoma without meningitis, and tuberculosis affecting the.
866 856 1645 1496 1069 252 1197 54 797 1526 1027 809 20 1539 648 151 756 1085 450 702 422 140 1042 321 1592 248 118 1049 210 503 773 416